Showing posts with label neurons. Show all posts
Showing posts with label neurons. Show all posts

Saturday, May 23, 2020

Echoes In The Braincase

One of the perks of a digital life is it is possible to present oneself to others neatly giftwrapped, and even add a rumpled bow of modesty and self-deprecation. One can think about it. Engineer it. Why, not too long ago one of you fine commenters here said I was "smart."

This is not so easy to pull off in person. And it's particularly hard to do in the presence of younger people. And I don't know what happened, but there are more and more of them around all the time.

I am well tolerated by the younger people in my life, all of whom I cherish. Now they are smart as hell. They have interesting opinions and different perspectives. I like to listen to them and every now and then I like to snap back with something witty. Problem is, a lot of the witty zone coincides with "things I just thought of five seconds ago." And things that happened five seconds ago live in a sort of quickly escaping vapor. I usually remember the first few words of my witty remark, but then I stick in placeholder grunts, hoping the rest of my thought will stroll by, but sometimes it doesn't, and then I have to say "I lost it there, but it'll come back."

The young people give me a fond and indulgent smile and assure me it will come back, even though it won't, and they know that by now. It's embarrassing. But they're so darn nice. "She's slipping," I see in their thought balloons, but you can see smiley emoticons in there too. I can't refute it. The whole thing has led me to be a better listener, or look just like one. I don't enjoy people witnessing my thoughts evaporate. Acting like I'm listening keeps me from looking as foolish, and is a good idea anyway.

I'm not actually listening. I am at first, but then I start thinking of something else altogether, usually a scene in a novel, or a reminiscence, or the state of the world, and my only connection to the conversation at that point is the attentive look on my face that I hope is still pointed in the correct direction. AND THIS IS WHEN I'M TALKING TO INTERESTING PEOPLE.

Authentic Old Person, With Bran
I'm not as embarrassed around people my own age. We're all kind of a mess. True, in my case some of them watch my neurons failing to connect and secretly put it down to the beer, but they understand anyway. If it wasn't the beer, it'd be something else.

There's a theory going around among older people that this phenomenon has something to do with having one's head so filled with wisdom that some of it needs to be off-loaded, and we have gained insight into what is important to keep and what is not. This is, of course, self-serving baldercookies. The fact is, if there were any more dead air in our brains our neurons wouldn't even touch each other.

Herewith a real dialog example:

     Me: "I'm trying to think of that word. You know, that word? That means, like, you really enjoy something, but it isn't anything you did yourself."

     Person: "Plagiarism?"

     Me: "No, no, more like something...vicarious." 

     Person: "Hmm. Vicarious?"

     Me: "Yeah! That's it! Thanks!" [bounces away]

     Person: [listens for head rattle]

Yes. That really happened. Probably. I do write fiction. It's either real or it's not, I don't remember.

Wednesday, January 30, 2019

Your Brain Is Playing Telephone

As a writer, I have observed that my output improves dramatically if I pause now and then to play Solitaire. It is so fruitful that I no longer even worry I'm wasting time, and I just go ahead and play whenever the mood hits.

A typical session might go as follows: black queen on red king, black six on red seven, turn, turn, OMG Camilla needs to be kidnapped and Hattie totally loses her shit in the next scene, three on ace.

It's reliable and cheaper than running a hot shower all day, which is the other way to produce ideas. But I've been at a loss to understand how it works.

In order to understand how creativity works, or any thought process at all, you must know a little about neurotransmission. Fortunately, that's exactly the amount I do know about neurotransmission.

Neurotransmitters are chemicals that poot out of the pointy axon end of a neuron and get gobbled up by the fluffy dendrite end of the next neuron over. It's the way they communicate. Without neurotransmitters, all our cells would just be a jumbled collection jostling each other on the platform, wondering when the train would arrive. But with neurotransmitters, our cells are lined up and whispering to each other in sequence, such that "Take your hand off the burner" eventually arrives in the spinal cord as "Tag Old Stan in the bunghole."

The first named neurotransmitter was discovered in 1921 by a guy named Otto, who got to name it. He called it Vagusstoff, but he was wrong, it turned out to be acetylcholine. Anyway, ol' Otto suspended two beating frog hearts in saline solution and molested one of them, causing it to slow down, and then the other one slowed down too, even though it was not otherwise involved. Also, all the frogs within a ten-mile radius dug deeper down into the mud.

The neurotransmitters in the brain cross over a gap between neurons called a synapse (Greek for "hole in the head"). There are gobs of neurons in the brain, and if you have a very small head like I do, they're packed in really tight. In addition to the neurons, there are even more cells called glia. They are not well understood but appear to be the support crew. They're either tightening bolts or sending out for sandwiches. In addition, they keep the neurons from rubbing up against each other and chafing.

It's not really known if the adult brain continues to create neurons. For a while there it was thought to, because this was observed in rat brains. People were really pumped about that, because they were pretty sure the standard neuron allotment wasn't cutting the mustard. Recently, it's come to light that this might be a rodent thing, and primates more or less make do with what they started with. This would be depressing were it not for the fact that we're already not doing much with the ones we have.

Synaptic pruning in process.
Furthermore, the adult brain is a sleeker model than the child brain, because during adolescence the brain undergoes something called "synaptic pruning," in which some 50% of the neuron connections are tidied up and disposed of. Theoretically this makes the adult brain more streamlined and efficient, but it's possible this is more of a process of civilization for the good of the species as a whole; a process by which humans transition from a life of unbridled masturbation to overeating, TV, and quiet desperation.

Back in oldener times, the brain was thought to be a wired-up electrical model. This was a daunting analysis in the days when people could devote hours to unscrewing every light on the Christmas tree to find the bad bulb. Nowadays we have a more nuanced understanding of brain processes, secure in the notion that if things go wrong we can always unplug, wait a few minutes, and plug back in.

And that's where the Solitaire comes in.

Saturday, August 16, 2014

Brain Frisbees

From Trousering Your Weasel

In our last post, we discussed how marijuana should not be combined with leftover turkey. So how does marijuana work? Well, it goes straight to the brain, because most of the time that's already the highest point in the body, and it travels through the blood-brain barrier. The blood-brain barrier exists in order to allow helpful items like glucose and hormones into the brain's fluid whilst keeping out the little fatties like bacteria and Botulinum that are up to no good. This is why you can inject Botox into your forehead to smooth out wrinkles without worrying about smoothing out the brain also, which you do not want. The active ingredients in marijuana are sleek, and they slither right on in, often illegally, where they wander around before settling down in a few specific areas of the brain: the basal blobular area, the antebellum, and the hippocampus. Fortunately, you're not using most of your brain most of the time. The basal blobular area is only there to keep the rest of the structure from caving in, and the antebellum sits at the back end to provide a cushion during whiplash events. The hippocampus is from the Latin for "the quad where the large animals hang out and play Frisbee," and naturally it's the go-to spot for pot.

The cool guys who were good at tossing a Frisbee could toke on a joint, tuck it under the lip of the Frisbee, and send it to the next guy, and that's sort of what happens in the brain, too. The hippocampus, like the rest of the brain, is lousy with neurons. There are more neurons in the brain than you can count, because you'd fall asleep before you finished. The neurons are single cells but they are not physically connected, and if they want to communicate, they have to throw neurotransmitter chemicals at each other. The pointy end (the axon) of one neuron winds up and tosses the chemical information to the branchy portion (the dendrites) of another. It's all Neurons In Space in there, and the neurons rely on each other's ability to toss and catch to get anything done at all. If the receiving neuron already has its hands full, the doobie of information falls out.

And that's what happens with the pot. The THC in marijuana acts like just another Frisbee and jams the receiving end of the neurons, which gums up their normal functions. Which, in the hippocampus, include your coordination, your short-term memory, and something else. Something-something. I used to know.

So anyway you might look at a pretty red flower and think: oh, wow, that is so red. And a moment later you're still looking at the flower but you think it's the first time you've really looked at it, and you think: oh, wow, that is so red. And so on, and so forth, until soon you are steeped in a redundancy of redness and you will be moved to write a poem about it, a poem without any of the coherence you'd have if you could properly recall your most recent thought. But that won't be clear until you look at the poem later.

And sometimes the fundamental incoherence of your now-compromised neurons starts to set off alarm bells until you're in a full-blown panic about the situation, no long able to track time, with your past disappearing before your eyes and your future, by extension, in doubt. That's what started to happen to me every time I smoked pot, which did not prevent me from continuing to smoke pot. Our generation had a lot invested in the idea that marijuana was harmless, and it took a while for me to consider that it might not be that good for me, personally. In reality, many of us had trouble with panic attacks and paranoia, but we didn't blame the pot. We blamed the Establishment, which was out to get us, a fact we could perceive most clearly when we were stoned.

(Kids are idiots. They'd be better off if they were stashed in the basement at age 13 and not let out until they were 30. Of course, a number of us did spend an equivalent amount of time in the basement, and didn't turn out that well. But it could have been so much worse.)