Showing posts with label Efudex. Show all posts
Showing posts with label Efudex. Show all posts

Saturday, November 17, 2012

Losing Face: Layer Two

Second installment. For the first part, click here.


May 16, 1980. Does he need the cream, too?
The next day I call again, hoping to score a different nurse, and I succeed. This just doesn't sound right. And it turns out it isn't right. There had been a miscommunication. The doctor tacks on a third week of treatment. I start again.

Given enough time, the magic cream will happily remove your whole face, but, in theory, it seeks out the faster-growing cells that are improperly motivated and burns them off first.  So a person applying said cream can expect portions of her skin to light up like the Milky Way. In my case, a number of areas of my face that I thought could be trusted to play quietly by themselves were actually up to no good. The magic cream lit up a stealth army of skin cells that had apparently been scheming to take me down all along. I am the captain of this here ship, and now I see there has been talk of mutiny. I intend to see to some plank-walkin'. I continue to apply the cream.

May 17, 1980
My chin has turned a blotchy plummy purple. To be fair, I have seen baby's bottoms that looked similar. My chin is not my favorite body part. It's been sinking into my doughy neck like a bon-bon on a pillow for years. As we know, the skin is the largest organ in the body, and I don't like to brag, but my neck is hung like a racehorse. I don't approve of this, but I had always thought that at least my chin looked comfy. Now I can see  it was just settling in to plot my downfall. I do remember the inciting incident. It was 1980. I was climbing Mt. Hood. People didn't do much sunscreen then, but our guide talked us into some zinc oxide, which I applied in an attractive smear across my cheeks and button nose. Worked good. The sun, however, was zinging off the snow and onto my lower face for hours. The next day I had blisters the size of voles hanging off my face. I got future-cancer in one day.

Week three is not too bad at first. Friends say nothing, but speculate privately about my diet. A few days later, passersby remain friendly and give Dave a nod of appreciation, assuming he is an evolved man who is drawn to inner beauty. On Day 24, they give him the raised eyebrow of suspicion. By Day 25, people snug their children to their sides and cross the street as I approach. The grocery clerk sprays antiseptic on his conveyor belt after I pay. A driver rolls down her window and lobs me a quarter. My face looks like a baby baboon's bottom. I decide to stay indoors out of consideration for others.

In the shower, my face shears off like a calf from a glacier and sludges up the drain.

At the end of the third week I call the nurse again. I feel worse. But I'm really not as miserable as I'm supposed to be. Should I keep going?

"Do you have any oozing?"

Yes! Yes I do!

"Is it honey-colored?"

Yes! Yes it is!

"Okay, that's probably a staph infection. Maybe you should see the doctor." And miracle of miracles, although appointments with my doctor are always two months out, she makes a slot available to me. I meet him between the ninth hole and the clubhouse.

The doctor said I can quit now. I walked away, a festering pus-bag with a bottle of antibiotics and a date in five months "to see how we did." I stopped well short of suicide, but murder is still on the table.

Wednesday, November 14, 2012

Losing Face: Layer One.

Before
The dermatologist has been breezily freezing off spots on my face for years. There's not a lot of chit-chat. He gives me a glance, blasts my spots, asks me if there's anything else I want him to look at. There's about half of me that I've never even seen, and I thought he might have volunteered to have a look, but the fact that he asks makes me feel like there's something sort of unseemly about it. So I say I guess not. Then he hands me a brochure about actinic keratoses and packs me off for another year. This summer he looked at my nose and said, breezily, "well, let's put some cream on that this year," and waved a photo of some violently pink people at me. "You might look a little sunburned for a while," he explained, "and then you'll have skin like a baby's bottom." Which can be good or bad, depending.

"I don't care how I look," I told him. "Is this spot precancerous or something?"

"Okay," he said, breezily. All righty then. Cream it is. Do I need to stay out of the sun?

"If you want," he said. "Whatever. My nurse can give you the details." And he's off.

One week
She said if I have a wedding to attend or something I could put this off until October, and I did, so I do. In the intervening months, my friend Vicki, who is doing the same basic treatment, clues me in, and I spend some time on the internet. Where I find out that the treatment, ideally, is supposed to turn your face into a flaming, pulpy, oozing mass of fried nerve endings and reduce you to hammering your fingers to distract yourself from the pain before it starts working. Various victims have posted progress photos on the web. Not much happens for the first few days and then spots light up here and there, mass together, and erupt. Helpless villagers flee. After a few weeks it is hard to distinguish between the eruptions and the marks left by attempts at self-strangulation. In the final photos the patients can be seen licking out the inside of the Oxycontin bottle. 40% can't bring themselves to continue to that therapeutic level. Sleeping is impossible, because of the screaming. The cream is called Efudex, or F.U. for short. Oh boy!

I put on my first application of cream. Twice a day for fourteen days, my doctor says. I know from my research that most people go three or even four weeks. I stare nervously at my face. We have started something here, and only great pain will resolve it. It is like finding yourself pregnant with a really ugly baby.

By day five, when most people begin to see spots and blotchiness, I look normal. I feel normal. Not until three days later do I begin to see the dawn of disfigurement. By day fourteen, when  I am supposed to quit, I don't look good, but nothing has erupted, nothing is oozing, nothing is crusting over, and--even according to my instructions--I have not reached the level of "therapeutic effect." I'm not even uncomfortable, just a little chapped. The doctor doesn't take calls. He's got a nurse for that. I call her.

"Yeah, you should probably keep going," she says, "but let me message the doctor. I'll get back to you."

Two weeks
She gets back to me. Nope: fourteen days it is. I should quit. He'll see me in six months.

"Are you sure?" I say. "I  mean, I've gone to all this trouble, and I'm willing to keep going. Am I supposed to lose all this time in? What if he tells me next time I have to start over? I'd have to murder him, and that wouldn't be good for either of us."

"I'm sure," she says. "It's right here in black and white." Well then. Can't argue with those colors.

So there it is. My dermatologist wants me to march right up to the edge of cancer with spears and cauldrons of boiling oil, and then stop short of the fortress and go booga booga booga. If my actinic keratoses are as easily startled as I am, it just might work.

To be continued.